Neuropsychologia 45 (2007), 630-638 Response variability in Attention Deficit Hyperactivity Disorder: Evidence for neuropsychological heterogeneity Katherine A. Kline Institute, Orangeburg, NY 10962, United States d Cognitive Neuroscience Laboratory, School of Behavioural Science, University of Melbourne, Australia Abstract Response time (RT) variability is a common finding in ADHD research.RT variability may reflect frontal cortex function and may be related to deficits in sustained attention.
It may be a useful source of information for students, medical professionals and those involved in education.
Although no immediate cure is in sight for it, a better understanding of ADHD through the research programmes gives us all more information on the role of the brain and effective treatments for the disorder. Robertson a School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Ireland b Schools of Psychiatry and Genetics and Trinity College Institute of Neuroscience, Trinity College Dublin, Ireland c Cognitive Neurophysiology Laboratory, Nathan S.
Treatments targeting ADHD symptoms are helpful for improving irritability in children with ADHD.
Moreover, irritability does not appear to influence the response to treatment of ADHD.
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Keywords: Sustained attention; Response time; Fast Fourier transform; Frontal cortex; Endophenotype © 2006 Elsevier Ltd. Neuropsychlogia 45 (2007) 2234-2245 Dissociation in performance of children with ADHD and high-functioning autism on a task of sustained attention Katherine A. The ADHD group showed clear deficits in response inhibition and sustained attention, through higher errors of commission and omission on both SART versions.
The HFA group showed no sustained attention deficits, through a normal number of omission errors on both SART versions.
Greater slow-frequency variability in response time and a slowing in mean response time by the ADHD group suggested impaired arousal processes.
The ADHD group showed greater fast-frequency variability in response time, indicative of impaired top-down control, relative to the HFA and control groups.